PLEUROPULMONARY BLASTOMA: MICROSCOPIC FINDINGS

• Solid areas:

1. Blastematous islands surrounded by a loose mesenchyma.

2. Nodules of cartilage with benign to overtly sarcomatous features.

3. Rhabdomyoblasts, individually or in groups.

4. Highly pleomorphic, anaplastic cells individually or in aggregates.

• None of the PPBs contained malignant glandular or immature tubular structures.

• IP stains:

1. Small primitive cells in solid areas: Vimentin, MSA, desmin.

2. Rhabdomyoblasts: MSA, desmin.3. Cartilaginous nodules: S-100.

4. Lining epithelium of cysts: CK, EMA.

Previous slide

Next slide

Back to first slide

View graphic version